Genetic Research Centers
Data Coordinating Center
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-kappaB and XBP1 binding sites.
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci