Stephan R. Targan

Latest

• Altered Intestinal ACE2 Levels Are Associated With Inflammation, Severe Disease, and Response to Anti-Cytokine Therapy in Inflammatory Bowel Disease
• Prevalence and Associations of Avascular Necrosis of the Hip in a Large Well-characterized Cohort of Patients With Inflammatory Bowel Disease
• Late-Onset Crohn's Disease Is A Subgroup Distinct in Genetic and Behavioral Risk Factors With UC-Like Characteristics
• Plasma N-Glycan Signatures Are Associated With Features of Inflammatory Bowel Diseases
• Colonic Phenotypes Are Associated with Poorer Response to Anti-TNF Therapies in Patients with IBD
• Association of Ribonuclease T2 Gene Polymorphisms With Decreased Expression and Clinical Characteristics of Severity in Crohn's Disease
• Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease
• Myeloid ATG16L1 Facilitates Host-Bacteria Interactions in Maintaining Intestinal Homeostasis
• The TNF family member TL1A induces IL-22 secretion in committed human Th17 cells via IL-9 induction
• Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease
• Perianal Crohn's Disease is Associated with Distal Colonic Disease, Stricturing Disease Behavior, IBD-Associated Serologies and Genetic Variation in the JAK-STAT Pathway
• A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition
• Ocular Manifestations in Inflammatory Bowel Disease Are Associated with Other Extra-intestinal Manifestations, Gender, and Genes Implicated in Other Immune-related Traits
• Characterization of genetic loci that affect susceptibility to inflammatory bowel diseases in African Americans
• Human NK cells licensed by killer Ig receptor genes have an altered cytokine program that modifies CD4+ T cell function
• Clinical, serologic, and genetic factors associated with pyoderma gangrenosum and erythema nodosum in inflammatory bowel disease patients
• Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohn's disease
• Multidimensional prognostic risk assessment identifies association between IL12B variation and surgery in Crohn's disease
• Assessing health status in inflammatory bowel disease using a novel single-item numeric rating scale
• Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
• Variants in ZNF365 isoform D are associated with Crohn's disease
• Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
• Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
• Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease
• Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease
• Genome-wide association identifies multiple ulcerative colitis susceptibility loci
• Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease
• Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study
• IL23R haplotypes provide a large population attributable risk for Crohn's disease
• Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
• Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis