Genetic Research Centers
Data Coordinating Center
A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition
Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies.
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-kappaB and XBP1 binding sites.
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci