Genetic Research Centers
Data Coordinating Center
John H. Brumell
Defects in NADPH Oxidase Genes NOX1 and DUOX2 in Very Early Onset Inflammatory Bowel Disease
Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease
NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2.
Single nucleotide polymorphisms that increase expression of the guanosine triphosphatase RAC1 are associated with ulcerative colitis.