Genetic Research Centers
Data Coordinating Center
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes.
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Common variants at five new loci associated with early-onset inflammatory bowel disease
Genetic variation in the familial Mediterranean fever gene (MEFV) and risk for Crohn's disease and ulcerative colitis
Common variants in the NLRP3 region contribute to Crohn's disease susceptibility
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
Assessment of reliability and validity of IBD phenotyping within the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics Consortium (IBDGC).