Genetic Research Centers
Data Coordinating Center
Charlie W. Lees
Fine-mapping inflammatory bowel disease loci to single-variant resolution
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2.
Single nucleotide polymorphisms that increase expression of the guanosine triphosphatase RAC1 are associated with ulcerative colitis.
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci