Azadeh Alikashani

Latest

• IBD-associated G protein-coupled receptor 65 variant compromises signalling and impairs key functions involved in inflammation
• Functional screen of inflammatory bowel disease genes reveals key epithelial functions
• Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis
• Genome-wide expression profiling implicates a MAST3-regulated gene set in colonic mucosal inflammation of ulcerative colitis patients